Progressive lenticular degeneration : a familial nervous disease assiociated with cirrhosis of the liver
[lieu de pubication inconnu] : [sans éditeur]
Université Paris Cité. BIU Santé Médecine
0197 - Page 488 - Physiological conclusions
0196 - Page 487 - Pathological conclusions
0195 - Page 486 - Chapter VIII.- Clinical conclusions
0187 - Page 478 - Chapter VII.- Syndrome of the corpus striatum
Fig. 99. Diagram to show the relations of the pyramidal and extrapyramidal systems, and the afferent cerebello-cortical system
0174 - Page 465 - Chapter VI.- Pathological physiology of the more important symptoms
0164 - Page 455 - Chapter V.- Nature and pathogenesis of the disease
0162 - Page sans numérotation - Table summarizing all the known cases of progressive lenticular degeneration
0142 - Page 435 - Chapter IV.- Synthetic study of the disease
Fig. 97. Naked-eye appearence of liver (case 6, National Hospital, 1869)/ Fig. 98. Transverse section of liver (case 6)
Fig. 95. Thyroid (case 3)/ Fig. 96. A minute vessel removed from degenerating lenticular area and cut separately (case 3)
Fig. 94. Continuity of so-called hypertrophying bilde-ducts xith columns of liver-cells (case 3)
Fig. 92. So-called hypertrophying bile ducts in cirrhotic tissue of liver (case 3) / Fig. 93. Regenerating liver-cells (case 3). Division of nuclei
Fig. 91. Liver (case 3). Haematoxylin-eosin. Healthy and degenerated liver-tissue
Fig. 89. Strip from precentral gyrus, left leg centre (case 3). Nissl. Normal betz-cells/ Fig. 90. Strip from precentral gyrus, left arm centre (case 3). Nissl. Normal betz-cells
Fig. 88. Horizontal section, right crus, somewhat lower than that of fig. 87 (case 3). Weigert
Fig. 86. Section of normal brain corresponding to that of fig. 85. Weigert/ Fig. 87. Sunthalamic region, left hemisphere (case 3). Weigert
Fig. 85. Horizontal section, right hemisphere (case 3). Weigert. Grossly atrophic putamen and globus pallidus
Fig. 84. Horizontal section, right hemisphere (case 3)
Fig. 82. A single lenticulo-striate vessel, removed and cut separately (case 3)/ Fig. 83. Macrophages from the degenerating area, left lenticular nucleus (case 3). Marchi. They are crammed with fatty granular débris
Fig. 81. Degenerated area, right putamen (case 3). Nissl.(x 500) Two degenrated nerve-cells, neuroglial cells, "Körnchenzellen", &c. Tissue breaking down
Fig. 80. Degenerated area, right putamen (case 3). Haematoxylin-eosin. A mass of amorphous neurological overgrowth, breaking down in some places
Fig. 78. Degenerated area of right putamen (case 3) / Fig. 79. Key to fig. 78
Fig. 77. Drawings of cut slabs of right basal ganglia (case 3). Natural size
Fig. 75. Crus cerebri (case 3). Weigert. Normal appearance/ Fig. 76. Cells of red nucleus (case 3). Nissl. Numbers of parasite glial cells round many of the nerve-cells
Fig. 74. Right hypoglossal nucleus (case 3). Nissl /
Fig. 72. Anterior horn cells, lumbar cord (case 3). Nissl / Fig. 73. Anterior horn cells, cervical cord (case 3). Nissl
Fig. 69. Cevical cord (case 3). Weigert/ Fig. 70. Dorsal cord (case 3). Weigert/ Fig. 71. Lumbard cord (case 3). Weigert
Fig. 68. Coupe d'éléction, hemispheres (case 3). Soft friable, disintegrated nucleus lenticularis on each side
Fig. 67. Coupe d'éléction. Normal brain of a youth who died of cirrhosis of the liver without nervous symptoms
Fig. 66. Coupe d'éléction, left hemispheres (case 3). Atrophic degeneration of lenticular nucleus
Fig. 65. Coupe d'éléction of hemispheres (case 3)
Fig. 62. Upper surface of cerebrum (case 3)/ Fig. 63. Under surface of cerebral hemispheres (case 3)
Fig. 61. Liver, transverse section (E.P., Case 3)
Fig. 60. Liver (E.P., Case 3). Under surface
Fig. 58. Vessels from the right putamen (case 2). Haematoxylin-van gieson. Normal walls. No small-cell infiltration/ Fig. 59. Transverse section of lenticulo-striate artery, removed from degenerated area and cut separately (case 2)
Fig. 56. Liver, transverse section (D.P.case 2). Natural size
Fig. 55. Liver under surface (D.P.case 2)
Fig. 53. Clumps of bacilli in cirrhotic liver tissue (case 1). Carbol gentian violet/ Fig. 54. Bacilli in neighbourhood of portal tract (case 1)
Fig. 51. Liver (case 1). Haematoxylin-van gieson. Irregular size of liver-nodules/ Fig. 52. Liver-cell divinding by an amitotic process.Haematoxylin eosin
Fig. 49. Degenerated blood-vessel from near margin of lenticular cavity (case 1) / Fig. 50. Oblique section from righte leg centre, paracentral lobule (case 1). Nissl. Normal Betz-cells
Fig. 48. Artery from globus pallidus. Weigert-Pal. Haematoxylin-van gieson. Normal walls (It has plug of bacilli in its lumen.)
Fig. 46. Margin of lenticular cavity (x60) Haematoxylin-van gieson/ Fig. 47. Degenerated fibres in globus pallidus. Weigert-Pal
Fig. 45. Photograph of maximum degenerated area (section imperfectly stained) to show situation of figs.46 and 47 (1=47; 2=46)
Fig. 44. Horizontal section n° C 39 (case 1) Weigert
Fig. 43. Horizontal section n° B31, left hemisphere (case 1) Weigert
Fig. 42. Vertico transverse section n°184 (case 1) Weigert-Pal. Posterior end of lenticular area
Fig. 41. Vertico transverse section n°148 (case 1) Weigert-Pal
Fig. 40. Correspond to lin 5-5 of fig. 37. Vertico-transverse. Posterior end of lenticular cavity is well shown. Note the normal sized optic thalamus
Fig. 39. Correspond to lin 4-4 of fig. 37. Vertico-transverse section. Cavity in place of lenticular nucleus. Internal capsule intact
Fig. 38.Slabs into which thr lrft hemisphere (case 1) was subdivided for the method of serial sections. Each block is 1cm. Thick. X-y as in fig.37
Fig. 37. Shows method of subdiving the right hemisphere (case 1) for examination in serial section. Each block is 1cm. Thick. X-y is the line of Marie's coupe d'election
Fig. 36. Crus cerebri (Case 1). Weigert-Pal
Fig. 34. Medulla (Case 1). Weigert-Pal/ Fig. 35 (Case 1). Hypoglossal nucleus, right side (Case 1). Nissl
Fig. 33. Anterior horn-cells, cervical region (Case 1). Nissl
Fig. 30.Cervical cord (Case 1). Weigert/ Fig. 31. Dorsal cord. Weigert/ Fig. 32. Lumbar cord (Case 1). Weigert
Fig. 29. Horizontal section through hemispheres (S.T., Case 1)
Fig. 28. Upper surface of brain (S.T., Case 1)
Fig. 27. Basal surface of brain (S.T., Case 1)
Fig. 25. Liver (S.T., Case 1), from above/ Fig. 26. Liver (S.T., Case 1). Transverse section
0070 - Page 363 - Chapter III.- Pathological finding in the personal cases
0067 - Page 360 - Résumé of the clinical History of case 4
Fig. 24. M. To. Note characteristic contacture-attitudes, tremor of right hand (the patient is grasping her nightdress with that hand in the endeavour to keep the limb as steady as possible), open mouth, vacant expression
Fig. 23. M. To (National Hospital, October, 1911). Characteristic fixed smile and retracted lips. Note intelligent expression of eyes. The patient is falling stiffly to the right
0059 - Page 352 - Résumé of the clinical History of case 3
Fig. 22 (june 4, 1910). Contracture-attitude of right hand
Fig. 21. E.P (june 4, 1910). Note vacant expression, open mouth, sialorrhoea, contractures
Fig. 19. E.P (June 4 , 1910). Note mouth, contractures, tremor of the hands
Fig. 18. Handwriting of E.P. after the onset of progressive lenticular degeneration
0045 - Page 338 - Résumé of the clinical History of case 2
Fig. 16. D.P.(national hospital, May 1906). Note how patient is leaning over the right side
Fig. 15. D.P. before the onset of the symptoms of progressive lenticular degeneration
0038 - Page 331 - Résumé of the clinical History of case 1
Fig. 14. Right arm and hand of S.T., showing contractures, and ressemblance of hand to that paralysis agitans
Fig. 13. Photographs of S. T., taken at Virginia Water. Characteristic appearance of face and upper limbs
Fig. 12. Photograph of S.T. before the onset of the symptoms of progressive lenticular degeneration
Fig. 11. Handwriting of S.T. when in hospital
0027 - Page 320 - Chapter II.- Clinical cases
Fig. 10. Wilhelm K (Homén.) Note the fixed, smiling expression, open mouth, contractures, and some emanciation (From Archiv f. Psychiat., 1892.)
Fig. 9. W.S.(Ormerod.) Bilateral softening in the putamen (From St. Bartholomew's Hospital Reports, 1890.)
Fig. 4. S. M (Gowers) From the original drawing in the notes of the case at the National Hospital / Fig. 5. S. M (Gowers) Photograph taken shortly before death, showing spastic smile, ontractures, and profound emaciation. From the original silver print (dated 1886), kindly lent to me by Dr.Thomas Wilson
Fig. 2-. S.M (Gowers.) Note the apparent indifference of the patient to the fact that his mouth is widely open. From the original in the notes at the National Hospital/ Fig. 3-. S.M (Gowers.) From the original drawing in the notes of the case at the National Hospital
Fig. 1. S.M (Gowers.) The tremors, spasticity, contractures, &co, are well seen. From one of the original silver prints (date 1886) kindly lent to me by Dr. Thomas Wilson
0007 - Page 300 - Chapter I.- Historical